40^th Global Summit and Expo on Vaccines & Immunology May 18-19, 2020 Paris, France

Osaka, one of Japan's largest cities, lies on the south coast of western Honshu at the point where the River Yodo flows into the wide sweep of Osaka Bay, which opens out into the Pacific. Its location on the Yodo delta with its network of watercourses and canals spanned by more than a thousand bridges has, deservedly, earned Osaka the nickname of the "Venice of the East." While the origins of Osaka date back to the mythological early days of the Japanese Empire, today it is undoubtedly one of the most modern cities in Japan, boasting a futuristic skyline along with countless impressive examples of modern architecture. Its world-class status is cemented by its many cultural institutions, from its superb museums and art galleries to its ultra-modern entertainment, theater, and music venues, which together add up to an endless list of unique things to do.

When planning your itinerary (as well as considering where to stay), bear in mind that Osaka in fact has two significant city centers. If being close to the top dining, shopping, and entertainment experiences is an important factor, you'll want to spend time in the Minami, or "South" district. Kita ("North"), the traditional business center of Osaka, is certainly worth considering, and is catching up in terms of its shopping, dining, entertainment, and accommodation offerings. Whichever you choose (but be sure to at least visit both), you'll find an excellent transportation system as you go about your sightseeing and explore the best places to visit in the city. Consider traveling to this popular destination in the quieter seasons, such as winter. You'll avoid the crowds at the most popular attractions, and you'll get the chance to experience unique sights, such as seeing Osaka Castle shrouded in snow and lit up at night. Plan your sightseeing with our list of the top tourist attractions in Osaka.